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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Luebering-Rapoport pathway ： ウィキペディア英語版 Luebering-Rapoport pathway In biochemistry, the Luebering-Rapoport pathway (also called the Luebering-Rapoport shunt) is a metabolic pathway in mature erythrocytes involving the formation of 2,3-bisphosphoglycerate (2,3-BPG), which regulates oxygen release from hemoglobin and delivery to tissues. 2,3-BPG, the reaction product of the Luebering-Rapoport pathway was first described and isolated in 1925 by the Austrian biochemist Samuel Mitja Rapoport and his technical assistant Janet Luebering.〔R. Juel: ''2,3-Diphosphoglycerate: its role in health and disease.'' In: ''CRC Critical Reviews in Clinical Laboratory Sciences.'' 10(2)/1979. CRC Press, S. 113–146, 〕 : Through the Luebering-Rapoport pathway bisphosphoglycerate mutase catalyzes the transfer of a phosphoryl group from C1 to C2 of 1,3-BPG, giving 2,3-BPG. 2,3-bisphosphoglycerate, the most concentrated organophosphate in the erythrocyte, forms 3-PG by the action of bisphosphoglycerate phosphatase. The concentration of 2,3-BPG varies inversely with the hydrogen-ion concentration (), which is inhibitory to catalytic action of bisphosphoglyceromutase. ==References== 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Luebering-Rapoport pathway」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.